Roles of Innate Lymphoid Cells
نویسندگان
چکیده
منابع مشابه
Innate lymphoid cells
Purpose of review: The purpose of this article is to review recent advances in our understanding of innate lymphoid cell function and to speculate on how these cells may become activated and influence the immune response to allogeneic tissues and cells following transplantation. Recent findings: Innate lymphoid cells encompass several novel cell types whose wide ranging roles in the immune syst...
متن کاملHuman innate lymphoid cells.
Innate lymphoid cells (ILCs) are lymphoid cells that do not express rearranged receptors and have important effector and regulatory functions in innate immunity and tissue remodeling. ILCs are categorized into 3 groups based on their distinct patterns of cytokine production and the requirement of particular transcription factors for their development and function. Group 1 ILCs (ILC1s) produce i...
متن کاملHiJAKing Innate Lymphoid Cells?
The family of innate lymphoid cells (ILCs) consists of a heterogeneous group of cytokine-producing cells that have features in common with adaptive T helper (Th) cells. Cytokines acting through the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathways are key players in both Th and ILC biology. Observations in animal models, supported by evidence from humans, have ...
متن کاملrole of innate lymphoid cells in lung disease
innate lymphoid cells (ilcs) are identified as novel population of hematopoietic cells which protect the body by coordinating the innate immune response against a wide range of threats including infections, tissue damages and homeostatic disturbances. ilcs, particularly ilc2 cells, are found throughout the body including the brain. ilcs are morphologically similar to lymphocytes, express and re...
متن کامل[Innate lymphoid cells and asthma].
Asthma is a complex and heterogeneous disease with several phenotypes, including an allergic asthma phenotype characterized by TH2 cytokine production and associated with allergen sensitization and adaptive immunity. Asthma also includes nonallergic asthma phenotypes, such as asthma associated with exposure to air pollution, infection, or obesity, that require innate rather than adaptive immuni...
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ژورنال
عنوان ژورنال: Kagaku To Seibutsu
سال: 2015
ISSN: 0453-073X,1883-6852
DOI: 10.1271/kagakutoseibutsu.53.78